Alan Greenspan, who served as chair of the Federal Reserve for nearly two decades, died at the age of 100 on Monday.

The renowned economist, who was first nominated by President Ronald Reagan in 1987, died from complications of Parkinson’s Disease, his wife, veteran NBC News journalist Andrea Mitchell, said in a statement.

“He was a giant of a man who helped shape the U.S. economy for decades under presidents of both parties but was always honest in acknowledging his mistake,” Mitchell said in her statement. “To me he was my husband, who shaped my life from our very first date in 1984. He had ‘irrational exuberance’ for baseball, the Washington Commanders, tennis, golf, and music, especially jazz. He will be remembered for his brilliance and his kindness. Being his life partner was the joy of my life.”

Greenspan served as the head of the United States’ central bank from 1987 until he retired in 2006 after working under four presidents: Reagan, George H.W. Bush, Bill Clinton and George W. Bush. He has the second-longest tenure in the role, behind William McChesney Martin Jr., who served from 1951 to 1970.

This is a developing story. Check back for updates.

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