At least two people were killed in a collision between an Air Canada regional jet and a fire truck on a runway at LaGuardia Airport in New York City late Sunday night, officials said. The incident closed down one of the country’s busiest airports, causing cancellations and delays nationwide.

During a news conference early Monday, Port Authority Executive Director Kathryn Garcia said the pilot and co-pilot were killed when Air Canada Flight 8646 crashed into a Port Authority aircraft rescue and firefighting vehicle around 11:40 p.m. ET on Sunday.

The fire truck had been responding to a separate incident, Port Authority said in a statement.

Garcia said 41 people were transferred to local hospitals, including the two officers on board the fire truck. Nine people remain hospitalized with injuries considered “serious.” All 72 passengers aboard the aircraft have been accounted for, Garcia said.

The airport will be closed until at least 2 p.m. as the investigation into the collision continues, the Port Authority said early Monday.

The aircraft — a Jazz Aviation flight operating on behalf of Air Canada Express — had been cleared to land. The emergency vehicle had also received clearance from the control center to cross the runway to respond to a separate incident. Moments before the crash, an air controller could be heard on radio transmission trying to stop the emergency vehicle from continuing after clearance was given.

The National Transportation Safety Board is on site conducting an investigation.

The New York Police Department announced all streets and highway exits into the airport would be closed until further notice.

This is a developing story.

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